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NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts

NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_bioone_primary_10_1093_biolre_iox009

NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts

About this item

Full title

NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts

Publisher

Society for the Study of Reproduction

Journal title

Biology of reproduction, 2017, Vol.96 (4), p.831-842

Language

English

Formats

Publication information

Publisher

Society for the Study of Reproduction

More information

Scope and Contents

Contents

During pregnancy, fetal extravillous trophoblasts (EVT) play a key role in the regulation of maternal T cell and NK cell responses. EVT display a unique combination of human leukocyte antigens (HLA); EVT do not express HLA-A and HLA-B, but do express HLA-C, HLA-E, and HLA-G. The mechanisms establishing this unique HLA expression pattern have not be...

Alternative Titles

Full title

NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_bioone_primary_10_1093_biolre_iox009

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_bioone_primary_10_1093_biolre_iox009

Other Identifiers

ISSN

0006-3363

E-ISSN

1529-7268

DOI

10.1093/biolre/iox009

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