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Crowdsourced mapping extends the target space of kinase inhibitors

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Crowdsourced mapping extends the target space of kinase inhibitors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2019_12_31_891812

Crowdsourced mapping extends the target space of kinase inhibitors

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Publisher

Cold Spring Harbor Laboratory

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Scope and Contents

Contents

Despite decades of intensive search for compounds that modulate the activity of particular targets, there are currently small-molecules available only for a small proportion of the human proteome. Effective approaches are therefore required to map the massive space of unexplored compound-target interactions for novel and potent activities. Here, we...

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Full title

Crowdsourced mapping extends the target space of kinase inhibitors

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Record Identifier

TN_cdi_biorxiv_primary_2019_12_31_891812

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2019_12_31_891812

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2019.12.31.891812

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