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Molecular Determinants of Liquid Demixing and Amyloidogenesis in Human CPEB3

Molecular Determinants of Liquid Demixing and Amyloidogenesis in Human CPEB3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2020_06_02_129783

Molecular Determinants of Liquid Demixing and Amyloidogenesis in Human CPEB3

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Full title

Molecular Determinants of Liquid Demixing and Amyloidogenesis in Human CPEB3

Publisher

Cold Spring Harbor Laboratory

Journal title

bioRxiv, 2020-06

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Publication information

Publisher

Cold Spring Harbor Laboratory

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Scope and Contents

Contents

The cytoplasmic polyadenylation element-binding protein 3 (CPEB3), is an RNA-binding protein which in its soluble state is localized in membraneless neuronal RNA granules keeping target mRNAs in a repressed state. The stimulus-dependent aggregation of CPEB3 activates target mRNAs translation, a central event for the maintenance of long-term memory-...

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Full title

Molecular Determinants of Liquid Demixing and Amyloidogenesis in Human CPEB3

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Record Identifier

TN_cdi_biorxiv_primary_2020_06_02_129783

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2020_06_02_129783

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E-ISSN

2692-8205

DOI

10.1101/2020.06.02.129783

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