Abstract To understand the role of host genetic variation in infection by SARS-CoV and influenza A virus we developed the Collaborative Cross Founder Expression Analysis (CCFEA), a shiny visualization tool using public RNAseq data from the collaborative cross (CC) founder strains (A/J, C57BL/6J, 129s1/SvImJ, NOD/ShILtJ, NZO/HILtJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ) that underwent infection by either virus, linked with genetic analyses to define loci linked to infection, immunity, and disease phenotypes. Individual gene expression data is displayed across founders, viral infections and days post infection. View this table: * View inline * View popup * Download powerpoint Competing Interest Statement The authors have declared no competing interest. Footnotes * ↵* Department of Immunology and the Center for Innate Immunity and Immune Disease (CIIID), University of Washington, Seattle, Washington, USA. * ↵** Department of Genetics, University of North Carolina at Chapel Hill, North Carolina, USA. * ↵*** Department of Biomedical Informatics and Medical Education (BIME), University of Washington, Seattle, Washington, USA. * http://shiny.galelab.org/Founder_Gene_Analysis.shiny/...

Collaborative Cross Founder Expression Analysis (CCFEA)

10.1101/2021.03.04.422591