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Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency b...

Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2021_05_13_443985

Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment

About this item

Full title

Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Ectopic gene expression is an indispensable tool in biology and medicine, but is often limited by the low efficiency of DNA transfection. We previously reported that depletion of the autophagy receptor p62/SQSTM1 enhances DNA transfection efficiency by preventing the degradation of transfected DNA. Therefore, p62 is a potential target for drugs to...

Alternative Titles

Full title

Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_biorxiv_primary_2021_05_13_443985

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2021_05_13_443985

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2021.05.13.443985

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