Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency b...
Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Ectopic gene expression is an indispensable tool in biology and medicine, but is often limited by the low efficiency of DNA transfection. We previously reported that depletion of the autophagy receptor p62/SQSTM1 enhances DNA transfection efficiency by preventing the degradation of transfected DNA. Therefore, p62 is a potential target for drugs to...
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Microtubule inhibitors identified through non-biased screening enhance DNA transfection efficiency by delaying p62-dependent ubiquitin recruitment
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TN_cdi_biorxiv_primary_2021_05_13_443985
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2021_05_13_443985
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2021.05.13.443985