Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni
Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni
About this item
Full title
Author / Creator
Publisher
Cold Spring Harbor Laboratory
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor Laboratory
Subjects
More information
Scope and Contents
Contents
Schistosoma mansoni histone deacetylase 8 (SmHDAC8) is a privileged target for drug discovery. Invalidation of its transcription by RNAi leads to impaired survival of the worms in infected mice and its inhibition causes cell apoptosis and death. To determine why it is a promising therapeutic target the study of the currently unknown cellular signal...
Alternative Titles
Full title
Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_biorxiv_primary_2021_05_26_445767
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2021_05_26_445767
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.05.26.445767
