PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection
PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection
About this item
Full title
Author / Creator
Qi, Chunyun , Pang, Daxin , Kang, Yang , Jiao, Shuyu , Wu, Heyong , Zhao, Chuheng , Hu, Lanxin , Li, Feng , Zhou, Jian , Yang, Lin , Lv, Dongmei , Tang, Xiaochun , Ouyang, Hongsheng and Xie, Zicong
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Classical swine fever virus (CSFV), pathogen of classic swine fever, has caused severe economic losses worldwide. Poly (rC)-binding protein 1 (PCBP1), interacting with Npro of CSFV, plays a vital role in CSFV growth. Here, our research is the first report to generate PCBP1 knockout pigs via gene editing technology. The PCBP1 knockout pigs exhibited...
Alternative Titles
Full title
PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_biorxiv_primary_2021_12_23_474075
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2021_12_23_474075
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2021.12.23.474075
