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Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis a...

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_03_16_532898

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

About this item

Full title

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Metabolic pathways are plastic and rapidly change in response to stress or perturbation. Current metabolic profiling techniques require lysis of many cells, complicating the tracking of metabolic changes over time after stress in rare cells such as hematopoietic stem cells (HSCs). Here, we aimed to identify the key metabolic enzymes that define dif...

Alternative Titles

Full title

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_biorxiv_primary_2023_03_16_532898

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_03_16_532898

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2023.03.16.532898

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