DDHD2 interacts with STXBP1 to mediate long-term memory via the generation of myristic acid
DDHD2 interacts with STXBP1 to mediate long-term memory via the generation of myristic acid
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Author / Creator
Akefe, Isaac O. , Matthews, Benjamin , Saber, Saber H. , Venkatesh, Bharat G. , Gormal, Rachel S. , Blackmore, Daniel G. , Sieriecki, Emma , Gambin, Yann , Bertran-Gonzalez, Jesus , Michaels, Alysee A. , Xue, Mingshan , Cravatt, Benjamin , Joensuu, Merja , Wallis, Tristan P. and Meunier, Frédéric A.
Publisher
Cold Spring Harbor Laboratory
Journal title
Language
English
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Publisher
Cold Spring Harbor Laboratory
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Scope and Contents
Contents
The phospholipid and free fatty acid (FFA) composition of neuronal membranes plays a crucial role in learning and memory, but the mechanisms through which neuronal activity affects the brain’s lipid landscape remain largely unexplored. Saturated FFAs, particularly myristic acid (C14:0), strongly increase during neuronal stimulation and memory acqui...
Alternative Titles
Full title
DDHD2 interacts with STXBP1 to mediate long-term memory via the generation of myristic acid
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Record Identifier
TN_cdi_biorxiv_primary_2023_05_11_540316
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_05_11_540316
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2023.05.11.540316