CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC
CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Sorafenib is commonly utilized in the management of advanced hepatocellular carcinoma (HCC). However, its efficacy in extending patients' survival is hindered by the development of drug resistance. By employing protein posttranslational modification (PTM) omics, including acetylome, phosphoproteome, and ubiquitinome, in conjunction with genome-wide...
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CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC
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TN_cdi_biorxiv_primary_2023_12_14_571783
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_12_14_571783
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2023.12.14.571783