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CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC

CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_12_14_571783

CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC

About this item

Full title

CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Sorafenib is commonly utilized in the management of advanced hepatocellular carcinoma (HCC). However, its efficacy in extending patients' survival is hindered by the development of drug resistance. By employing protein posttranslational modification (PTM) omics, including acetylome, phosphoproteome, and ubiquitinome, in conjunction with genome-wide...

Alternative Titles

Full title

CCT3 drives Sorafenib resistance by inhibiting TFRC-mediated iron uptake in HCC

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_biorxiv_primary_2023_12_14_571783

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2023_12_14_571783

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2023.12.14.571783

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