Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Stran...
Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors
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Publisher
Cold Spring Harbor Laboratory
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Language
English
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Publisher
Cold Spring Harbor Laboratory
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Scope and Contents
Contents
Persons with HIV (PWH) receiving integrase (IN) strand transfer inhibitors (INSTIs) have been reported to experience virologic failure (VF) in the absence of resistance mutations in IN. We previously reported that mutations in the viral nucleocapsid (NC) are selected in the presence of the INSTI dolutegravir (DTG) and confer levels of INSTI resista...
Alternative Titles
Full title
Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors
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Record Identifier
TN_cdi_biorxiv_primary_2025_05_17_654662
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_biorxiv_primary_2025_05_17_654662
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2025.05.17.654662
