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Inhibition of hypoxia-inducible carbonic anhydraseIX enhances hexokinase II inhibitor-induced hepato...

Inhibition of hypoxia-inducible carbonic anhydraseIX enhances hexokinase II inhibitor-induced hepato...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_chongqing_primary_38696057

Inhibition of hypoxia-inducible carbonic anhydraseIX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis

About this item

Full title

Inhibition of hypoxia-inducible carbonic anhydraseIX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis

Journal title

中国药理学报:英文版, 2011, Vol.32 (7), p.912-920

Language

English

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Scope and Contents

Contents

Aim: The hypoxic condition within large or infiltrative hypovascular tumors produces intracellular acidification, which could activate many signaling pathways and augment cancer cell growth and invasion. Carbonic anhydrase-IX (CA-IX) is an enzyme lowering pH. This study is to examine whether hypoxia induces CA-IX in hepatocellular carcinoma (HCC) c...

Alternative Titles

Full title

Inhibition of hypoxia-inducible carbonic anhydraseIX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_chongqing_primary_38696057

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_chongqing_primary_38696057

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

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