Revealing a steroid receptor ligand as a unique PPARγ 3gonist
Revealing a steroid receptor ligand as a unique PPARγ 3gonist
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English
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Peroxisome proliferator-activated receptor gamma (PPARy) regulates metabolic homeostasis and is a molecular target for anti-diabetic drugs. We report here the identification of a steroid receptor ligand, RU-486, as an unexpected PPARy agonist, thereby uncovering a novel signaling route for this steroid drug. Similar to rosiglitazone, RU- 486 modula...
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Revealing a steroid receptor ligand as a unique PPARγ 3gonist
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TN_cdi_chongqing_primary_41470963
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_chongqing_primary_41470963
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1001-0602
E-ISSN
1748-7838