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Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery

Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_cristin_nora_10852_64645

Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery

About this item

Full title

Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery

Journal title

LC GC North America, 2017

Language

Norwegian

More information

Scope and Contents

Contents

Fluorescence polarization (FP) is a highly regarded technique for studying drug–protein interactions, but has limited value regarding protein mixtures. As a novel approach to drug target discovery, the possibility of combining FP with liquid chromatography (LC) was explored. Nondenaturing protein LC principles such as size-exclusion chromatography...

Alternative Titles

Full title

Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_cristin_nora_10852_64645

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_cristin_nora_10852_64645

Other Identifiers

ISSN

1527-5949

E-ISSN

1939-1889

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