Mucosal or systemic microbiota exposures shape the B cell repertoire
Mucosal or systemic microbiota exposures shape the B cell repertoire
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Author / Creator
Li, Hai , Limenitakis, Julien P. , Greiff, Victor , Yilmaz, Bahtiyar , Schären, Olivier , Urbaniak, Camilla , Zünd, Mirjam , Lawson, Melissa A. E. , Young, Ian D. , Rupp, Sandra , Heikenwälder, Mathias , McCoy, Kathy D. , Hapfelmeier, Siegfried , Ganal-Vonarburg, Stephanie C. and Macpherson, Andrew J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Colonization by the microbiota causes a marked stimulation of B cells and induction of immunoglobulin, but mammals colonized with many taxa have highly complex and individualized immunoglobulin repertoires
1
,
2
. Here we use a simplified model of defined transient exposures to different microbial taxa in germ-free mice
3
to decon...
Alternative Titles
Full title
Mucosal or systemic microbiota exposures shape the B cell repertoire
Authors, Artists and Contributors
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Record Identifier
TN_cdi_cristin_nora_10852_83677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_cristin_nora_10852_83677
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2564-6
