De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25– cells
De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25– cells
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United States: National Acad Sciences
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Language
English
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United States: National Acad Sciences
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Antigen-specificity is a hallmark of adaptive T cell-mediated immune responses. CD4 + CD25 + FOXP3 + regulatory T cells (T R ) also require activation through the T cell receptor for function. Although these cells require antigen-specific activation, they are generally able to suppress bystander T cell responses once activated. This raises the poss...
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Full title
De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25– cells
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TN_cdi_crossref_citationtrail_10_1073_pnas_0407691102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0407691102
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0407691102
