Crystal Structure and Mechanistic Determinants of SARS Coronavirus Nonstructural Protein 15 Define a...
Crystal Structure and Mechanistic Determinants of SARS Coronavirus Nonstructural Protein 15 Define an Endoribonuclease Family
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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The ≈30-kb coronavirus (+)RNA genome is replicated and transcribed by a membrane-bound replicase complex made up of 16 viral nonstructural proteins (nsp) with multiple enzymatic activities. The complex includes an RNA endonuclease, NendoU, that is conserved among nidoviruses but no other RNA virus, making it a genetic marker of this virus order. Ne...
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Crystal Structure and Mechanistic Determinants of SARS Coronavirus Nonstructural Protein 15 Define an Endoribonuclease Family
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TN_cdi_crossref_citationtrail_10_1073_pnas_0601708103
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0601708103
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0601708103
