Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement
Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Cellular DNA damage triggers the DNA damage response pathway and leads to enforcement of cell cycle checkpoints, which are essential for the maintenance of genomic integrity and are activated in early stages of tumorigenesis. A special feature of prostate cancer is its high incidence and multifocality. To address the functionality of DNA damage che...
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Full title
Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement
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TN_cdi_crossref_citationtrail_10_1073_pnas_0609299104
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0609299104
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0609299104