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Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0609299104

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

About this item

Full title

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (17), p.7211-7216

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cellular DNA damage triggers the DNA damage response pathway and leads to enforcement of cell cycle checkpoints, which are essential for the maintenance of genomic integrity and are activated in early stages of tumorigenesis. A special feature of prostate cancer is its high incidence and multifocality. To address the functionality of DNA damage che...

Alternative Titles

Full title

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_0609299104

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0609299104

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0609299104

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