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RETRACTED: Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted gen...

RETRACTED: Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted gen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0710433105

RETRACTED: Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted genome modification

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Full title

RETRACTED: Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted genome modification

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (28), p.9576-9581

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Scope and Contents

Contents

The inefficiency of gene modification by homologous recombination can be overcome by the introduction of a double-strand break (DSB) in the target. Engineering the endonucleases needed, however, remains a challenging task that limits widespread application of nuclease-driven gene modification. We report here that conjugates of orthophenanthroline (...

Alternative Titles

Full title

RETRACTED: Triplex-forming oligonucleotide–orthophenanthroline conjugates for efficient targeted genome modification

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Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_0710433105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0710433105

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0710433105

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