Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Neural precursor cells (NPCs) differentiate into neurons, astrocytes, and oligodendrocytes in response to intrinsic and extrinsic changes. Notch signals maintain undifferentiated NPCs, but the mechanisms underlying the neuronal differentiation are largely unknown. We show that SIRT1, an NAD⁺-dependent histone deacetylase, modulates neuronal differe...
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Full title
Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
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TN_cdi_crossref_citationtrail_10_1073_pnas_0800612105
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0800612105
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0800612105
