Dependence of antibody-mediated presentation of antigen on FcRn
Dependence of antibody-mediated presentation of antigen on FcRn
About this item
Full title
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The neonatal Fc receptor for IgG (FcRn) is a distant member of the MHC class I protein family. It binds IgG and albumin in a pH-dependent manner and protects these from catabolism by diverting them from a degradative fate in lysosomes. In addition, FcRn-mediated IgG transport across epithelial barriers is responsible for the transmission of IgG fro...
Alternative Titles
Full title
Dependence of antibody-mediated presentation of antigen on FcRn
Authors, Artists and Contributors
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Record Identifier
TN_cdi_crossref_citationtrail_10_1073_pnas_0801717105
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_0801717105
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0801717105
