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Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1004623107

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

About this item

Full title

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (38), p.16613-16618

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development and function of thymic epithelial cells (TECs) of the mouse. TECs are of endodermal origin; they initially express Foxn1 and give rise to orthotopic (thoracic) and additional (cervical) thymi. Using Foxn1-directed cytoabla...

Alternative Titles

Full title

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_1004623107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1004623107

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1004623107

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