Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral mic...
Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral microRNAs
About this item
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Author / Creator
Santhakumar, Diwakar , Forster, Thorsten , Laqtom, Nouf N. , Fragkoudis, Rennos , Dickinson, Paul , Abreu-Goodger, Cei , Manakov, Sergei A. , Choudhury, Nila Roy , Griffiths, Samantha J. , Vermeulen, Annaleen , Enright, Anton J. , Dutia, Bernadette , Kohl, Alain , Ghazal, Peter , Buck, Amy H. and Pace, Norman R.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Although the functional parameters of microRNAs (miRNAs) have been explored in some depth, the roles of these molecules in viral infections remain elusive. Here we report a general method for global analysis of miRNA function that compares the significance of both overexpressing and inhibiting each mouse miRNA on the growth properties of different...
Alternative Titles
Full title
Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral microRNAs
Authors, Artists and Contributors
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Record Identifier
TN_cdi_crossref_citationtrail_10_1073_pnas_1008861107
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1008861107
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1008861107
