Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Dietary absorption is a major way for mammals to obtain cholesterol, which is mediated by Niemann-Pick C1-like 1 (NPC1L1) via vesicular endocytosis. One fundamental question in this process is how free cholesterol is efficiently taken up through the internalization of NPC1L1. Using exogenously expressed NPC1L1-EGFP, we show that the lipid raft prot...
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Full title
Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
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TN_cdi_crossref_citationtrail_10_1073_pnas_1014434108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1014434108
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1014434108
