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HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR path...

HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR path...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1018859108

HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

About this item

Full title

HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2736-2741

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Multiple factors including long-term treatment with tamoxifen are involved in the development of selective estrogen receptor (ER) modulator resistance in ERα-positive breast cancer. Many underlying molecular events that confer resistance are known but a unifying theme is yet to be revealed. In this report, we provide evidence that HOXB7 overexpress...

Alternative Titles

Full title

HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_1018859108

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1018859108

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1018859108

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