Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response
Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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SRC-3 is an important coactivator of nuclear receptors including the retinoic acid (RA) receptor α. Most of SRC-3 functions are facilitated by changes in the posttranslational code of the protein that involves mainly phosphorylation and ubiquitination. We recently reported that SRC-3 is degraded by the proteasome in response to RA. Here, by using a...
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Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response
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TN_cdi_crossref_citationtrail_10_1073_pnas_1102572108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1102572108
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1102572108
