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Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1222534110

Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

About this item

Full title

Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (30), p.E2792-E2801

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The 5′-untranslated region (5′-UTR) of mRNAs contains elements that affect expression, yet the rules by which these regions exert their effect are poorly understood. Here, we studied the impact of 5′-UTR sequences on protein levels in yeast, by constructing a large-scale library of mutants that differ only in the 10 bp preceding the translational s...

Alternative Titles

Full title

Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_1222534110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1222534110

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1222534110

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