Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Chromatin immunoprecipitation (ChIP) is the gold-standard technique for localizing nuclear proteins in the genome. We used ChIP, in combination with deep sequencing (Seq), to study the genome-wide distribution of the Silent information regulator (Sir) complex in Saccharomyces cerevisiae . We analyzed ChIP-Seq peaks of the Sir2, Sir3, and Sir4 silen...
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Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
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TN_cdi_crossref_citationtrail_10_1073_pnas_1316064110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1316064110
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1316064110
