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Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1321200111

Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

About this item

Full title

Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3661-3661

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Tumor suppressor Pbx-regulating protein-1 (
Prep1
) and myeloid ecotropic viral integration site-1 (
Meis1
) oncogene are transcriptional regulators, which bind to the same partner, pre–B-cell leukemia homeobox-1 (
Pbx1
).
Meis1
overexpression induces tumorigenesis in
Prep1
i/i
mouse embryonic fibroblasts, which is...

Alternative Titles

Full title

Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_1321200111

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1321200111

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1321200111

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