Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte...
Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition
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Author / Creator
Aikio, Mari , Elamaa, Harri , Vicente, David , Izzi, Valerio , Kaur, Inderjeet , Seppinen, Lotta , Speedy, Helen E. , Kaminska, Dorota , Kuusisto, Sanna , Sormunen, Raija , Heljasvaara, Ritva , Jones, Emma L. , Muilu, Mikko , Jauhiainen, Matti , Pihlajamäki, Jussi , Savolainen, Markku J. , Shoulders, Carol C. and Pihlajaniemi, Taina
Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Collagen XVIII is an evolutionary conserved ubiquitously expressed basement membrane proteoglycan produced in three isoforms via two promoters (P). Here, we assess the function of the N-terminal, domain of unknown function/frizzled-like sequences unique to medium/long collagen XVIII by creating P- specific null mice. P2 -null mice, which only produ...
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Full title
Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition
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TN_cdi_crossref_citationtrail_10_1073_pnas_1405879111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1405879111
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1405879111