PP2A methylation controls sensitivity and resistance to β-amyloid–induced cognitive and electrophysi...
PP2A methylation controls sensitivity and resistance to β-amyloid–induced cognitive and electrophysiological impairments
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Elevated levels of the β-amyloid peptide (Aβ) are thought to contribute to cognitive and behavioral impairments observed in Alzheimer’s disease (AD). Protein phosphatase 2A (PP2A) participates in multiple molecular pathways implicated in AD, and its expression and activity are reduced in postmortem brains of AD patients. PP2A is regulated by protei...
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Full title
PP2A methylation controls sensitivity and resistance to β-amyloid–induced cognitive and electrophysiological impairments
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TN_cdi_crossref_citationtrail_10_1073_pnas_1521018113
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_1521018113
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1521018113
