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Hematopoietic and Lung Abnormalities in Mice with a Null Mutation of the Common β Subunit of the Rec...

Hematopoietic and Lung Abnormalities in Mice with a Null Mutation of the Common β Subunit of the Rec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_92_21_9565

Hematopoietic and Lung Abnormalities in Mice with a Null Mutation of the Common β Subunit of the Receptors for Granulocyte-Macrophage Colony- Stimulating Factor and Interleukins 3 and 5

About this item

Full title

Hematopoietic and Lung Abnormalities in Mice with a Null Mutation of the Common β Subunit of the Receptors for Granulocyte-Macrophage Colony- Stimulating Factor and Interleukins 3 and 5

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1995-10, Vol.92 (21), p.9565-9569

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Gene targeting was used to create mice with a null mutation of the gene encoding the common β subunit (βC) of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3; multi-CSF), and interleukin 5 (IL-5) receptor complexes (βC
-/-mice). High-affinity binding of GM-CSF was abolished in βC
-/-bone marrow cells, while...

Alternative Titles

Full title

Hematopoietic and Lung Abnormalities in Mice with a Null Mutation of the Common β Subunit of the Receptors for Granulocyte-Macrophage Colony- Stimulating Factor and Interleukins 3 and 5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1073_pnas_92_21_9565

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1073_pnas_92_21_9565

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.92.21.9565

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