A Novel Mechanism of Resistance Against Antimicrobial Peptides Involves Extracellular Sensing Couple...
A Novel Mechanism of Resistance Against Antimicrobial Peptides Involves Extracellular Sensing Coupled with Membrane Remodeling Mediated by a Single Protein
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Publisher
US: Oxford University Press
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Language
English
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Publisher
US: Oxford University Press
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Abstract
Background
The three-component regulatory system LiaFSR is a major mediator of resistance against daptomycin (DAP) and antimicrobial peptides (AMP) in enterococci. The main target of the LiaR response regulator is a cluster of three genes (designated liaXYZ). LiaX has distinct C- and N-terminal domains and is highly secreted in DAP-r...
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Full title
A Novel Mechanism of Resistance Against Antimicrobial Peptides Involves Extracellular Sensing Coupled with Membrane Remodeling Mediated by a Single Protein
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TN_cdi_crossref_citationtrail_10_1093_ofid_ofx163_194
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1093_ofid_ofx163_194
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ISSN
2328-8957
E-ISSN
2328-8957
DOI
10.1093/ofid/ofx163.194
