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Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1098_rstb_2017_0362

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

About this item

Full title

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

Publisher

England: The Royal Society

Journal title

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-07, Vol.373 (1750), p.20170362-20170362

Language

English

Formats

Publication information

Publisher

England: The Royal Society

More information

Scope and Contents

Contents

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in developed countries. An in vitro NAFLD model would permit mechanistic studies and enable high-throughput therapeutic screening. While hepatic cancer-derived cell lines are a convenient, renewable resource, their genomic, epigenomic and functional alterations mean...

Alternative Titles

Full title

Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1098_rstb_2017_0362

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1098_rstb_2017_0362

Other Identifiers

ISSN

0962-8436

E-ISSN

1471-2970

DOI

10.1098/rstb.2017.0362

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