High Glucose Promotes Tumor Invasion and Increases Metastasis-Associated Protein Expression in Human...
High Glucose Promotes Tumor Invasion and Increases Metastasis-Associated Protein Expression in Human Lung Epithelial Cells by Upregulating Heme Oxygenase-1 via Reactive Oxygen Species or the TGF-β1/PI3K/Akt Signaling Pathway
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Author / Creator
Kang, Xiaowen , Kong, Fanwu , Wu, Xiaomei , Ren, Yeping , Wu, Shijie , Wu, Kaiming , Jiang, Zhe and Zhang, Wei
Publisher
Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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Language
English
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Publisher
Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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Background: Growing evidence indicates that heme oxygenase-1 (HO-1) is up-regulated in malignancies and subsequently alters tumor aggressiveness and various cancer-related factors, such as high glucose (HG) levels. HO-1 expression can be induced when glucose concentrations are above 25 mM; however, the role of HO-1 in lung cancer patients with diab...
Alternative Titles
Full title
High Glucose Promotes Tumor Invasion and Increases Metastasis-Associated Protein Expression in Human Lung Epithelial Cells by Upregulating Heme Oxygenase-1 via Reactive Oxygen Species or the TGF-β1/PI3K/Akt Signaling Pathway
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Record Identifier
TN_cdi_crossref_citationtrail_10_1159_000373928
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1159_000373928
Other Identifiers
ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000373928
