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Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Recep...

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Recep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1159_000441280

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

About this item

Full title

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

Publisher

Basel, Switzerland: S. Karger AG

Journal title

International archives of allergy and immunology, 2015-01, Vol.168 (1), p.13-24

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and are n...

Alternative Titles

Full title

Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_citationtrail_10_1159_000441280

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1159_000441280

Other Identifiers

ISSN

1018-2438

E-ISSN

1423-0097

DOI

10.1159/000441280

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