Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Recep...
Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors
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Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and are n...
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Full title
Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors
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TN_cdi_crossref_citationtrail_10_1159_000441280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1159_000441280
Other Identifiers
ISSN
1018-2438
E-ISSN
1423-0097
DOI
10.1159/000441280