Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nu...
Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos
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Author / Creator
Zhang, Zhiren , Zhai, Yanhui , Ma, Xiaoling , Zhang, Sheng , An, Xinglan , Yu, Hao and Li, Ziyi
Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Basel, Switzerland: S. Karger AG
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Background/Aims: Aberrantly high levels of H3K4me3, caused by incomplete epigenetic reprogramming, likely cause a low efficiency of somatic cell nuclear transfer (SCNT). Smal molecule inhibitors aimed at epigenetic modification can be used to improve porcine SCNT embryo development. In this study, we examined the effects of MM-102, an H3K4 histone...
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Full title
Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos
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Record Identifier
TN_cdi_crossref_citationtrail_10_1159_000487579
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1159_000487579
Other Identifiers
ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000487579
