An inducible knock-out mouse to model cell-autonomous role of PTEN in initiating endometrial, prosta...
An inducible knock-out mouse to model cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
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PTEN is one of the most frequently mutated tumor suppressor genes in human cancers. The role of PTEN in carcinogenesis has been validated by knockout mouse models. PTEN heterozygous mice develop neoplasms in multiple organs. Unfortunately, the embryonic lethality of biallelic excision of PTEN has inhibited the study of complete PTEN deletion in the...
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An inducible knock-out mouse to model cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
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TN_cdi_crossref_citationtrail_10_1242_dmm_011445
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1242_dmm_011445
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1754-8403
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1754-8411
DOI
10.1242/dmm.011445
