Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacte...
Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis
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Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute inflammation as a result of impaired secretion of proinflammatory cytokines by macrophages. To investigate the impaired cytokine secretion, we performed transcriptomic analysis in macrophages and identified a subgroup of CD patients with...
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Optineurin deficiency contributes to impaired cytokine secretion and neutrophil recruitment in bacteria driven colitis
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TN_cdi_crossref_citationtrail_10_1242_dmm_020362
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1242_dmm_020362
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1754-8403
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1754-8411
DOI
10.1242/dmm.020362
