p53-independent DUX4 pathology
p53-independent DUX4 pathology
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Full title
p53-independent DUX4 pathology
Author / Creator
Journal title
Disease models & mechanisms, 2017-01
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Contents
FSHD is a genetically dominant myopathy caused by mutations that disrupt repression of the normally silent DUX4 gene, which encodes a transcription factor that has been shown to interfere with myogenesis when misexpressed at very low levels in myoblasts, and to cause cell death when overexpressed at high levels. A previous report using adeno-associ...
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Full title
p53-independent DUX4 pathology
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TN_cdi_crossref_citationtrail_10_1242_dmm_030064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_citationtrail_10_1242_dmm_030064
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.030064
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