The CK 1ε/ SIAH1 axis regulates AXIN 1 stability in colorectal cancer cells
The CK 1ε/ SIAH1 axis regulates AXIN 1 stability in colorectal cancer cells
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Author / Creator
Yan, Mengfang , Su, Zijie , Pang, Xiaoyi , Wang, Hanbin , Dai, Han , Ning, Jiong , Liu, Shanshan , Sun, Qi , Song, Jiaxing , Zhao, Xibao and Lu, Desheng
Journal title
Language
English
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Contents
Casein kinase 1ε (CK1ε) and axis inhibitor 1 (AXIN1) are crucial components of the β‐catenin destruction complex in canonical Wnt signaling. CK1ε has been shown to interact with AXIN1, but its physiological function and role in tumorigenesis remain unknown. In this study, we found that CK1δ/ε inhibitors significantly enhanced AXIN1 protein level in...
Alternative Titles
Full title
The CK 1ε/ SIAH1 axis regulates AXIN 1 stability in colorectal cancer cells
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Record Identifier
TN_cdi_crossref_primary_10_1002_1878_0261_13624
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1002_1878_0261_13624
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.13624
