Targeting the CLK 2/ SRSF 9 splicing axis in prostate cancer leads to decreased ARV 7 expression
Targeting the CLK 2/ SRSF 9 splicing axis in prostate cancer leads to decreased ARV 7 expression
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English
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In advanced prostate cancer (PC), in particular after acquisition of resistance to androgen receptor (AR) signaling inhibitors (ARSI), upregulation of AR splice variants compromises endocrine therapy efficiency. Androgen receptor splice variant‐7 (ARV7) is clinically the most relevant and has a distinct 3′ untranslated region (3′UTR) compared to th...
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Targeting the CLK 2/ SRSF 9 splicing axis in prostate cancer leads to decreased ARV 7 expression
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TN_cdi_crossref_primary_10_1002_1878_0261_13728
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1002_1878_0261_13728
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1574-7891
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1878-0261
DOI
10.1002/1878-0261.13728