Epstein–Barr Virus/Human Vector Provides High-Level, Long-Term Expression of α1-Antitrypsin in Mice
Epstein–Barr Virus/Human Vector Provides High-Level, Long-Term Expression of α1-Antitrypsin in Mice
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Publisher
Elsevier Inc
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Language
English
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Elsevier Inc
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Contents
We have constructed plasmid DNA vectors that contain Epstein–Barr virus (EBV) sequences and the human gene (SERPINA1) encoding α1-Antitrypsin (AAT). We demonstrate that a plasmid carrying the full SERPINA1 on a 19-kb genomic fragment and the EBV gene EBNA1 and its family of repeats binding sites undergoes efficient extrachromosomal replication in d...
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Full title
Epstein–Barr Virus/Human Vector Provides High-Level, Long-Term Expression of α1-Antitrypsin in Mice
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TN_cdi_crossref_primary_10_1006_mthe_2001_0429
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1006_mthe_2001_0429
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1006/mthe.2001.0429
