Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequenc...
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair-derived artifacts as residual errors
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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To improve the accuracy and the cost-efficiency of next-generation sequencing in ultralow-frequency mutation detection, we developed the Paired-End and Complementary Consensus Sequencing (PECC-Seq), a PCR-free duplex consensus sequencing approach. PECC-Seq employed shear points as endogenous barcodes to identify consensus sequences from the overlap...
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Full title
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair-derived artifacts as residual errors
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TN_cdi_crossref_primary_10_1007_s00204_020_02832_0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00204_020_02832_0
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ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-020-02832-0
