A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with rel...
A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia
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Author / Creator
BERNSTEIN, S. H , FAY, J , FRANKEL, S , CHRISTIANSEN, N , BAER, M. R , JACOBS, C , BLOSCH, C , HANNA, R and HERZIG, G
Publisher
Berlin: Springer
Journal title
Language
English
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Publication information
Publisher
Berlin: Springer
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Scope and Contents
Contents
The recombinant human interleukin-1 receptor (rhu IL-1R) is a soluble truncated form of the type 1 full-length membrane-bound receptor that binds IL-1 with identical affinity to that of the membrane form. As such, it may have clinical potential by sequestering IL-1, thereby preventing it from binding to its membrane-bound receptor and eliciting a b...
Alternative Titles
Full title
A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia
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Record Identifier
TN_cdi_crossref_primary_10_1007_s002800050874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s002800050874
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s002800050874