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A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with rel...

A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with rel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s002800050874

A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia

About this item

Full title

A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia

Publisher

Berlin: Springer

Journal title

Cancer chemotherapy and pharmacology, 1999, Vol.43 (2), p.141-144

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

The recombinant human interleukin-1 receptor (rhu IL-1R) is a soluble truncated form of the type 1 full-length membrane-bound receptor that binds IL-1 with identical affinity to that of the membrane form. As such, it may have clinical potential by sequestering IL-1, thereby preventing it from binding to its membrane-bound receptor and eliciting a b...

Alternative Titles

Full title

A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1007_s002800050874

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s002800050874

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s002800050874

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