Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv in...
Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction
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Publisher
Tokyo: Springer Japan
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Language
English
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Publisher
Tokyo: Springer Japan
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Contents
Background
Periostin is a matricellular protein that serves as a ligand for integrins and is required for tissue remodeling and fibrosis. We investigated the role of periostin in hepatic fibrosis and the mechanisms involved.
Methods
Primary hepatic stellate cells (HSCs) and the HSC-immortalized cell line LX2 were used to study the profibro...
Alternative Titles
Full title
Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction
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Record Identifier
TN_cdi_crossref_primary_10_1007_s00535_016_1206_0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00535_016_1206_0
Other Identifiers
ISSN
0944-1174
E-ISSN
1435-5922
DOI
10.1007/s00535-016-1206-0