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Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv in...

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00535_016_1206_0

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction

About this item

Full title

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction

Publisher

Tokyo: Springer Japan

Journal title

Journal of gastroenterology, 2016-12, Vol.51 (12), p.1161-1174

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

Background
Periostin is a matricellular protein that serves as a ligand for integrins and is required for tissue remodeling and fibrosis. We investigated the role of periostin in hepatic fibrosis and the mechanisms involved.
Methods
Primary hepatic stellate cells (HSCs) and the HSC-immortalized cell line LX2 were used to study the profibro...

Alternative Titles

Full title

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1007_s00535_016_1206_0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1007_s00535_016_1206_0

Other Identifiers

ISSN

0944-1174

E-ISSN

1435-5922

DOI

10.1007/s00535-016-1206-0

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