Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltag...
Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
T cell activation triggers large calcium fluxes. Flavell and colleagues show tonic calcium signaling via Ca
v
1.4-β3 channels are needed for the survival and homeostasis of naive CD8
+
T cells.
The survival of T lymphocytes requires sustained, Ca
2+
influx–dependent gene expression. The molecular mechanism that governs sustaine...
Alternative Titles
Full title
Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels
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Record Identifier
TN_cdi_crossref_primary_10_1038_ni_1793
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_ni_1793
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1793
