Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in...
Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in a hyperoxia-based mouse model of bronchopulmonary dysplasia
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Background:
Caffeine is widely used to manage apnea of prematurity, and reduces the incidence of bronchopulmonary dysplasia (BPD). Deregulated transforming growth factor (TGF)-β signaling underlies arrested postnatal lung maturation in BPD. It is unclear whether caffeine impacts TGF-β signaling or postnatal lung development in affected lungs.
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Full title
Caffeine administration modulates TGF-β signaling but does not attenuate blunted alveolarization in a hyperoxia-based mouse model of bronchopulmonary dysplasia
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TN_cdi_crossref_primary_10_1038_pr_2017_21
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_pr_2017_21
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ISSN
0031-3998
E-ISSN
1530-0447
DOI
10.1038/pr.2017.21
