Cryo-EM structures of apo and antagonist-bound human Cav3.1
Cryo-EM structures of apo and antagonist-bound human Cav3.1
About this item
Full title
Author / Creator
Zhao, Yanyu , Huang, Gaoxingyu , Wu, Qiurong , Wu, Kun , Li, Ruiqi , Lei, Jianlin , Pan, Xiaojing and Yan, Nieng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Among the ten subtypes of mammalian voltage-gated calcium (Ca
v
) channels, Ca
v
3.1–Ca
v
3.3 constitute the T-type, or the low-voltage-activated, subfamily, the abnormal activities of which are associated with epilepsy, psychiatric disorders and pain
1
–
5
. Here we report the cryo-electron microscopy structures of hu...
Alternative Titles
Full title
Cryo-EM structures of apo and antagonist-bound human Cav3.1
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1038_s41586_019_1801_3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1038_s41586_019_1801_3
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1801-3
