Developing an in silico model of the modulation of base excision repair using methoxyamine for more...
Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics
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Full title
Author / Creator
Publisher
England: The Institution of Engineering and Technology
Journal title
Language
English
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Publisher
England: The Institution of Engineering and Technology
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Scope and Contents
Contents
Base excision repair (BER) is a major DNA repair pathway involved in the processing of exogenous non-bulky base damages from certain classes of cancer chemotherapy drugs as well as ionising radiation (IR). Methoxyamine (MX) is a small molecule chemical inhibitor of BER that is shown to enhance chemotherapy and/or IR cytotoxicity in human cancers. I...
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Full title
Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics
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Record Identifier
TN_cdi_crossref_primary_10_1049_iet_syb_2011_0045
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1049_iet_syb_2011_0045
Other Identifiers
ISSN
1751-8849
E-ISSN
1751-8857
DOI
10.1049/iet-syb.2011.0045
